Differential Signaling by Protease-Activated Receptors: Implications for Therapeutic Targeting

Protease-activated receptors (PARs) are a family of four G protein-coupled receptors that exhibit increasingly appreciated differences in signaling and regulation both within and between the receptor class. By nature of their proteolytic self-activation mechanism, PARs have unique processes of rece...

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Bibliographic Details
Main Authors: Tejminder S. Sidhu, Shauna L. French, Justin R. Hamilton
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/15/4/6169