Glycerol restores heat-induced p53-dependent apoptosis of human glioblastoma cells bearing mutant p53

<p>Abstract</p> <p>Background</p> <p>We have previously reported that glycerol acts as a chemical chaperone to restore the expression of WAF1 in some human cancer cell lines bearing mutant p53. Since the expression of WAF1 is up-regulated by activated wildtype p53, glyc...

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Bibliographic Details
Main Authors: Ohnishi Ken, Ohnishi Takeo, Takahashi Akihisa
Format: Article
Language:English
Published: BMC 2002-04-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/2/6