Recellularization of rat liver: An in vitro model for assessing human drug metabolism and liver biology.

Liver-like organoids that recapitulate the complex functions of the whole liver by combining cells, scaffolds, and mechanical or chemical cues are becoming important models for studying liver biology and drug metabolism. The advantages of growing cells in three-dimensional constructs include enhance...

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Bibliographic Details
Main Authors: Matthew J Robertson, Benjamin Soibam, Jacqueline G O'Leary, Luiz C Sampaio, Doris A Taylor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5788381?pdf=render