Exosomes derived from HIV-1-infected cells promote growth and progression of cancer via HIV TAR RNA

Exosomes derived from HIV-1-infected cells promote growth and progression of cancer via HIV TAR RNA

HIV patients have an increased risk of developing non-AIDS-defining cancers but the molecular mechanisms underlying this predisposition are unclear. Here the authors show that exosomes secreted by HIV-infected T cells or isolated from the blood of HIV-positive patients, stimulate oncogenic propertie...

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Bibliographic Details
Main Authors: Lechuang Chen, Zhimin Feng, Hong Yue, Douglas Bazdar, Uri Mbonye, Chad Zender, Clifford V. Harding, Leslie Bruggeman, Jonathan Karn, Scott F. Sieg, Bingcheng Wang, Ge Jin
Format: Article
Language:English
Published: Nature Publishing Group 2018-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07006-2

Internet

https://doi.org/10.1038/s41467-018-07006-2

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