Exosomes derived from HIV-1-infected cells promote growth and progression of cancer via HIV TAR RNA
HIV patients have an increased risk of developing non-AIDS-defining cancers but the molecular mechanisms underlying this predisposition are unclear. Here the authors show that exosomes secreted by HIV-infected T cells or isolated from the blood of HIV-positive patients, stimulate oncogenic propertie...
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Bibliographic Details
| Main Authors: |
Lechuang Chen,
Zhimin Feng,
Hong Yue,
Douglas Bazdar,
Uri Mbonye,
Chad Zender,
Clifford V. Harding,
Leslie Bruggeman,
Jonathan Karn,
Scott F. Sieg,
Bingcheng Wang,
Ge Jin |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2018-11-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-018-07006-2
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