GSK-3β, a double-edged sword in Nrf2 regulation: Implications for neurological dysfunction and disease [version 1; referees: 2 approved]
In the past decade, it has become evident that glycogen synthase kinase 3β (GSK-3β) modulates the nuclear factor erythroid 2-related factor 2 (Nrf2) oxidative stress response. GSK-3β functions as an inhibitor, both directly in the activation and indirectly in the post-induction of Nrf2. The incidenc...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
F1000 Research Ltd
2018-07-01
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| Series: | F1000Research |
| Online Access: | https://f1000research.com/articles/7-1043/v1 |