Development of small diameter nanofiber tissue engineered arterial grafts.

The surgical repair of heart and vascular disease often requires implanting synthetic grafts. While synthetic grafts have been successfully used for medium-to-large sized arteries, applications for small diameter arteries (<6 mm) is limited due to high rates of occlusion by thrombosis. Our object...

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Bibliographic Details
Main Authors: Hirotsugu Kurobe, Mark W Maxfield, Shuhei Tara, Kevin A Rocco, Paul S Bagi, Tai Yi, Brooks Udelsman, Zhen W Zhuang, Muriel Cleary, Yasuko Iwakiri, Christopher K Breuer, Toshiharu Shinoka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0120328