Development, Phenotypic Characterization and Genomic Analysis of a Francisella tularensis Panel for Tularemia Vaccine Testing

Development, Phenotypic Characterization and Genomic Analysis of a Francisella tularensis Panel for Tularemia Vaccine Testing

Francisella tularensis is one of several biothreat agents for which a licensed vaccine is needed to protect against this pathogen. To aid in the development of a vaccine protective against pneumonic tularemia, we generated and characterized a panel of F. tularensis isolates that can be used as chall...

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Bibliographic Details
Main Authors: Beth A. Bachert, Joshua B. Richardson, Kevin D. Mlynek, Christopher P. Klimko, Ronald G. Toothman, David P. Fetterer, Andrea E. Luquette, Kitty Chase, Jessica L. Storrs, Ashley K. Rogers, Christopher K. Cote, David A. Rozak, Joel A. Bozue
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Microbiology
Subjects:
Francisella tularensis
vaccine
tularemia
Francisella pathogenicity island
virulence
mouse
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.725776/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2021.725776/full

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