Individual and Combined Impact of Oxygen and Oxygen Transporter Supplementation during Kidney Machine Preservation in a Porcine Preclinical Kidney Transplantation Model

Individual and Combined Impact of Oxygen and Oxygen Transporter Supplementation during Kidney Machine Preservation in a Porcine Preclinical Kidney Transplantation Model

Marginal kidney graft preservation in machine perfusion (MP) is well-established. However, this method requires improvement in order to mitigate oxidative stress during ischemia-reperfusion, by using oxygenation or an O<sub>2</sub> carrier with anti-oxidant capacities (hemoglobin of the...

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Bibliographic Details
Main Authors: Abdelsalam Kasil, Sebastien Giraud, Pierre Couturier, Akbar Amiri, Jerome Danion, Gianluca Donatini, Xavier Matillon, Thierry Hauet, Lionel Badet
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
dynamic/machine perfusion
oxygen
hemoglobin
ischemia
kidney transplantation
Online Access:https://www.mdpi.com/1422-0067/20/8/1992

Internet

https://www.mdpi.com/1422-0067/20/8/1992

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