Distribution and radiosensitizing effect of cholesterol-coupled Dbait molecule in rat model of glioblastoma.

Distribution and radiosensitizing effect of cholesterol-coupled Dbait molecule in rat model of glioblastoma.

Glioma is the most aggressive tumor of the brain and the most efficient treatments are based on radiotherapy. However, tumors are often resistant to radiotherapy due to an enhanced DNA repair activity. Short and stabilized DNA molecules (Dbait) have recently been proposed as an efficient strategy to...

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Bibliographic Details
Main Authors: Nicolas Coquery, Nicolas Pannetier, Régine Farion, Aurélie Herbette, Leire Azurmendi, Didier Clarencon, Stéphane Bauge, Véronique Josserand, Claire Rome, Jean-Luc Coll, Jian-Sheng Sun, Emmanuel L Barbier, Marie Dutreix, Chantal C Remy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3398898?pdf=render

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http://europepmc.org/articles/PMC3398898?pdf=render

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