Cathepsins in the Pathophysiology of Mucopolysaccharidoses: New Perspectives for Therapy

Cathepsins (CTSs) are ubiquitously expressed proteases normally found in the endolysosomal compartment where they mediate protein degradation and turnover. However, CTSs are also found in the cytoplasm, nucleus, and extracellular matrix where they actively participate in cell signaling, protein proc...

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Bibliographic Details
Main Authors: Valeria De Pasquale, Anna Moles, Luigi Michele Pavone
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/4/979