TP53 Gene Mutations in Tumor Cells of Patients with Aggressive B-Cell Lymphomas

TP53 Gene Mutations in Tumor Cells of Patients with Aggressive B-Cell Lymphomas

Background. TP53 gene mutations impede cell apoptosis and lead to additional oncogenic events contributing to tumor progression. Aim. To assess TP53 gene mutation rate in patients with high-grade B-cell lymphoma double-hit (HGBCL DH) and not otherwise specified (HGBL NOS); to analyse its relationsh...

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Bibliographic Details
Main Authors: AE Misyurina, SK Kravchenko, VA Misyurin, AM Kovrigina, AU Magomedova, EA Baryakh, FE Babaeva, AV Misyurin
Format: Article
Language:Russian
Published: Practical Medicine Publishing House 2019-05-01
Series:Kliničeskaâ onkogematologiâ
Subjects:
high-grade b-cell lymphoma double-hit
high-grade b-cell lymphoma not otherwise specified
tp53 mutation in tumor cells
translocation involving c–myc gene locus
Online Access: http://bloodjournal.ru/wp-content/uploads/2019/06/3.pdf

Internet

http://bloodjournal.ru/wp-content/uploads/2019/06/3.pdf

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