Retroactive maintains cuticle integrity by promoting the trafficking of Knickkopf into the procuticle of Tribolium castaneum.

Molting, or the replacement of the old exoskeleton with a new cuticle, is a complex developmental process that all insects must undergo to allow unhindered growth and development. Prior to each molt, the developing new cuticle must resist the actions of potent chitinolytic enzymes that degrade the o...

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Bibliographic Details
Main Authors: Sujata S Chaudhari, Yasuyuki Arakane, Charles A Specht, Bernard Moussian, Karl J Kramer, Subbaratnam Muthukrishnan, Richard W Beeman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3561106?pdf=render