Spatiotemporal constraints on optogenetic inactivation in cortical circuits
Optogenetics allows manipulations of genetically and spatially defined neuronal populations with excellent temporal control. However, neurons are coupled with other neurons over multiple length scales, and the effects of localized manipulations thus spread beyond the targeted neurons. We benchmarked...
Main Authors: | Nuo Li, Susu Chen, Zengcai V Guo, Han Chen, Yan Huo, Hidehiko K Inagaki, Guang Chen, Courtney Davis, David Hansel, Caiying Guo, Karel Svoboda |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-11-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/48622 |
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