LANA oligomeric architecture is essential for KSHV nuclear body formation and viral genome maintenance during latency.

LANA oligomeric architecture is essential for KSHV nuclear body formation and viral genome maintenance during latency.

The molecular basis for the formation of functional, higher-ordered macro-molecular domains is not completely known. The Kaposi's Sarcoma-Associated Herpesvirus (KSHV) genome forms a super-molecular domain structure during latent infection that is strictly dependent on the DNA binding of the vi...

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Bibliographic Details
Main Authors: Alessandra De Leo, Zhong Deng, Olga Vladimirova, Horng-Shen Chen, Jayaraju Dheekollu, Abram Calderon, Kenneth A Myers, James Hayden, Frederick Keeney, Benedikt B Kaufer, Yan Yuan, Erle Robertson, Paul M Lieberman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC6364946?pdf=render

Internet

http://europepmc.org/articles/PMC6364946?pdf=render

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