The interaction of p130Cas with PKN3 promotes malignant growth

Protein p130Cas constitutes an adaptor protein mainly involved in integrin signaling downstream of Src kinase. Owing to its modular structure, p130Cas acts as a general regulator of cancer cell growth and invasiveness induced by different oncogenes. However, other mechanisms of p130Cas signaling lea...

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Bibliographic Details
Main Authors: Jakub Gemperle, Michal Dibus, Lenka Koudelková, Daniel Rosel, Jan Brábek
Format: Article
Language:English
Published: Wiley 2019-02-01
Series:Molecular Oncology
Subjects:
CAS
SH3
Src
Online Access:https://doi.org/10.1002/1878-0261.12401