Nerve growth factor protects against palmitic acid-induced injury in retinal ganglion cells

Nerve growth factor protects against palmitic acid-induced injury in retinal ganglion cells

Accumulating evidence supports an important role for nerve growth factor (NGF) in diabetic retinopathy. We hypothesized that NGF has a protective effect on rat retinal ganglion RGC-5 cells injured by palmitic acid (PA), a metabolic factor implicated in the development of diabetes and its complicatio...

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Bibliographic Details
Main Authors: Pan-shi Yan, Shu Tang, Hai-feng Zhang, Yuan-yuan Guo, Zhi-wen Zeng, Qiang Wen
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; RGC-5 cells; palmitic acid; nerve growth factor; apoptosis; PI3K; Akt; FoxO1; ERK1/2; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2016;volume=11;issue=11;spage=1851;epage=1856;aulast=Yan

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2016;volume=11;issue=11;spage=1851;epage=1856;aulast=Yan

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