Suppression of Nrf2 Activity by Chestnut Leaf Extract Increases Chemosensitivity of Breast Cancer Stem Cells to Paclitaxel

Suppression of Nrf2 Activity by Chestnut Leaf Extract Increases Chemosensitivity of Breast Cancer Stem Cells to Paclitaxel

Due to metastatic potential and drug resistance, cancer stem cells (CSCs) have become a critical target for the development of chemotherapeutic agents. Recent studies showed that CSCs highly express NF-E2-related factor 2 (Nrf2)-mediated antioxidant enzymes and thereby retain relatively low levels o...

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Bibliographic Details
Main Authors: Yaejin Woo, Jisun Oh, Jong-Sang Kim
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Nutrients
Subjects:
breast cancer
cancer stem cell
Nrf2
drug resistance
Castanea crenata
Online Access:https://www.mdpi.com/2072-6643/9/7/760

Internet

https://www.mdpi.com/2072-6643/9/7/760

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