How to Better Understand the Influence of Host Genetics on Developing an Effective Immune Response to Thoracic Cancers

How to Better Understand the Influence of Host Genetics on Developing an Effective Immune Response to Thoracic Cancers

Thoracic cancers pose a significant global health burden. Immune checkpoint blockade therapies have improved treatment outcomes, but durable responses remain limited. Understanding how the host immune system interacts with a developing tumor is essential for the rational development of improved trea...

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Bibliographic Details
Main Authors: Kiarash Behrouzfar, Kimberley Burton, Steve E. Mutsaers, Grant Morahan, Richard A. Lake, Scott A. Fisher
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
thoracic malignancies
tumor immune microenvironment
mesothelioma
Collaborative Cross
MexTAg
host genetics
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.679609/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.679609/full

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