Mechanism of parathyroid hormone-mediated suppression of calcification markers in human intervertebral disc cells

In degenerative intervertebral discs (IVD), type X collagen (COL X) expression (associated with hypertrophic differentiation) and calcification has been demonstrated. Suppression of COL X expression and calcification during disc degeneration can be therapeutic. In the present study we investigated t...

Full description

Bibliographic Details
Main Authors: P Madiraju, R Gawri, H Wang, J Antoniou, F Mwale
Format: Article
Language:English
Published: AO Research Institute Davos 2013-05-01
Series:European Cells & Materials
Subjects:
Online Access:http://www.ecmjournal.org/journal/papers/vol025/pdf/v025a19.pdf