A common SMAD7 variant is associated with risk of colorectal cancer: evidence from a case-control study and a meta-analysis.

<h4>Background</h4>A common genetic variant, rs4939827, located in SMAD7, was identified by two recent genome-wide association (GWA) studies to be strongly associated with the risk of colorectal cancer (CRC). However, the following replication studies yielded conflicting results.<h4&g...

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Main Authors: Qibin Song, Beibei Zhu, Weiguo Hu, Liming Cheng, Hongyun Gong, Bin Xu, Xiawen Zheng, Li Zou, Rong Zhong, Shengyu Duan, Wei Chen, Rui Rui, Jing Wu, Xiaoping Miao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22457752/pdf/?tool=EBI