AMP-activated protein kinase deficiency reduces ozone-induced lung injury and oxidative stress in mice

<p>Abstract</p> <p>Background</p> <p>Acute ozone exposure causes lung oxidative stress and inflammation leading to lung injury. At least one mechanism underlying the lung toxicity of ozone involves excessive production of reactive oxygen and nitrogen intermediates such...

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Bibliographic Details
Main Authors: Jean, Lancel Steve, Tiesset Hélène, Hulo Sébastien, Viollet Benoit, Sobaszek Annie, Nevière Rémi
Format: Article
Language:English
Published: BMC 2011-05-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/12/1/64