Genome-wide analysis of immune activation in human T and B cells reveals distinct classes of alternatively spliced genes.

Genome-wide analysis of immune activation in human T and B cells reveals distinct classes of alternatively spliced genes.

Alternative splicing of pre-mRNA is a mechanism that increases the protein diversity of a single gene by differential exon inclusion/exclusion during post-transcriptional processing. While alternative splicing is established to occur during lymphocyte activation, little is known about the role it pl...

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Bibliographic Details
Main Authors: Yevgeniy A Grigoryev, Sunil M Kurian, Aleksey A Nakorchevskiy, John P Burke, Daniel Campbell, Steve R Head, Jun Deng, Aaron B Kantor, John R Yates, Daniel R Salomon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2775942?pdf=render

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http://europepmc.org/articles/PMC2775942?pdf=render

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