T cell responses to human endogenous retroviruses in HIV-1 infection.

Human endogenous retroviruses (HERVs) are remnants of ancient infectious agents that have integrated into the human genome. Under normal circumstances, HERVs are functionally defective or controlled by host factors. In HIV-1-infected individuals, intracellular defense mechanisms are compromised. We...

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Bibliographic Details
Main Authors: Keith E Garrison, R Brad Jones, Duncan A Meiklejohn, Naveed Anwar, Lishomwa C Ndhlovu, Joan M Chapman, Ann L Erickson, Ashish Agrawal, Gerald Spotts, Frederick M Hecht, Seth Rakoff-Nahoum, Jack Lenz, Mario A Ostrowski, Douglas F Nixon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.0030165