Increased ectodomain shedding of cell adhesion molecule 1 from pancreatic islets in type 2 diabetic pancreata: correlation with hemoglobin A1c levels.

Pulmonary emphysema and type 2 diabetes mellitus (T2DM), both caused by lifestyle factors, frequently concur. Respectively, the diseases affect lung alveolar and pancreatic islet cells, which express cell adhesion molecule 1 (CADM1), an immunoglobulin superfamily member. Protease-mediated ectodomain...

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Bibliographic Details
Main Authors: Takao Inoue, Man Hagiyama, Azusa Yoneshige, Takashi Kato, Eisuke Enoki, Osamu Maenishi, Takaaki Chikugo, Masatomo Kimura, Takao Satou, Akihiko Ito
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4071031?pdf=render