Time course of VCAM-1 expression in reperfused myocardial infarction in swine and its relation to retention of intracoronary administered bone marrow-derived mononuclear cells.

Intracoronary infusion of autologous bone marrow-derived mononuclear cells (BMMNC), after acute myocardial infarction (AMI), has been shown to improve myocardial function. However, therapeutic efficacy is limited, possibly because cell retention rates are low, suggesting that optimization of cell re...

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Main Authors: André Uitterdijk, Bianca C W Groenendijk, Charlotte Gorsse-Bakker, Anna Panasewicz, Stefan Sneep, Dennie Tempel, Esther H van de Kamp, Daphne Merkus, Willem J van der Giessen, Dirk J Duncker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5476248?pdf=render