High-Resolution Crystal Structure of RpoS Fragment including a Partial Region 1.2 and Region 2 from the Intracellular Pathogen Legionella pneumophila

High-Resolution Crystal Structure of RpoS Fragment including a Partial Region 1.2 and Region 2 from the Intracellular Pathogen Legionella pneumophila

Legionella pneumophila RpoS (LpRpoS), an alternative sigma factor of RNA polymerase (RNAP), is essential for virulence and stress resistance. To investigate the mechanism of RpoS in the intracellular pathogen L. pneumophila, we determined the high-resolution crystal structure of the LpRpoS 95–195 co...

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Bibliographic Details
Main Authors: Nannan Zhang, Xiaofang Chen, Xiaojian Gong, Tao Li, Zhiyuan Xie, Muhammad Fazal Hameed, Mingzhu Wang, Honghua Ge
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Crystals
Subjects:
RpoS
crystal structure
Legionella pneumophila
intracellular pathogen
regulatory factor
Online Access:http://www.mdpi.com/2073-4352/8/2/54

Internet

http://www.mdpi.com/2073-4352/8/2/54

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