ABC-F Proteins Mediate Antibiotic Resistance through Ribosomal Protection
Members of the ABC-F subfamily of ATP-binding cassette proteins mediate resistance to a broad array of clinically important antibiotic classes that target the ribosome of Gram-positive pathogens. The mechanism by which these proteins act has been a subject of long-standing controversy, with two comp...
Main Authors: | Liam K. R. Sharkey, Thomas A. Edwards, Alex J. O’Neill |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2016-03-01
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Series: | mBio |
Online Access: | http://mbio.asm.org/cgi/content/full/7/2/e01975-15 |
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