Addition of Popular Exogenous Antioxidant Agent, PBN, to Culture Media May Be an Important Step to Optimization of Myogenic Stem/Progenitor Cell Preparation Protocol

Addition of Popular Exogenous Antioxidant Agent, PBN, to Culture Media May Be an Important Step to Optimization of Myogenic Stem/Progenitor Cell Preparation Protocol

The aim of the study was to modify human skeletal muscle-derived stem/progenitor cells (SkMDS/PCs) and demonstrate the optimal cell preparation protocol for application in post-infarction hearts. We used conditioned SkMDS/PC culture medium with α-phenyl-N-tert-butyl nitrone (PBN). SkMDS/PCs were cul...

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Bibliographic Details
Main Authors: Magdalena Nowaczyk, Agnieszka Malcher, Agnieszka Zimna, Wojciech Łabędź, Łukasz Kubaszewski, Wojciech Barczak, Błażej Rubiś, Natalia Rozwadowska, Maciej Kurpisz
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Antioxidants
Subjects:
α-phenyl-N-tert-butyl nitrone
heart failure
skeletal muscle derived stem cells
apoptosis
oxidative stress
post-infarction heart
Online Access:https://www.mdpi.com/2076-3921/10/6/959

Internet

https://www.mdpi.com/2076-3921/10/6/959

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