Gene specific modifications unravel ethanol and acetaldehyde actions

Ethanol is metabolized into acetaldehyde mainly by the action of alcohol dehydrogenase in the liver, while mainly by the action of catalase in the brain. Aldehyde dehydrogenase-2 metabolizes acetaldehyde into acetate in both organs. Gene specific modifications reviewed here show that an increased l...

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Bibliographic Details
Main Authors: YEDY eISRAEL, Mario eRivera-Meza, Eduardo eKarahanian, Maria Elena Quintanilla, Lutske eTampier, Paola eMorales, Mario eHerrera-Marschitz
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2013.00080/full