Real-time visualization of intratumoral necrosis using split-luciferase reconstitution by protein trans-splicing

Real-time visualization of intratumoral necrosis using split-luciferase reconstitution by protein trans-splicing

Necrosis, a form of cell death, occurs not only with the development of various diseases but also with a tumor tissue response to cancer treatment. Therefore, pursuing progress for cancer therapy through induction of necrosis may be one of the most effective approaches for cancer eradication. We her...

Full description

Bibliographic Details
Main Authors: Go Kagiya, Ayaka Sato, Ryohei Ogawa, Masanori Hatashita, Mana Kato, Makoto Kubo, Fumiaki Kojima, Fumitaka Kawakami, Yukari Nishimura, Naoya Abe, Fuminori Hyodo
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Therapy: Oncolytics
Subjects:
cell death
necrosis
intein
extein
protein trans-splicing
necrosis imaging reporter
Online Access:http://www.sciencedirect.com/science/article/pii/S237277052030173X

Internet

http://www.sciencedirect.com/science/article/pii/S237277052030173X

Similar Items