Levosimendan for patients with severely reduced left ventricular systolic function and/or low cardiac output syndrome undergoing cardiac surgery: a systematic review and meta-analysis

Abstract Background Previous studies have shown beneficial effects of levosimendan in high-risk patients undergoing cardiac surgery. Two large randomized controlled trials (RCTs), however, showed no advantages of levosimendan. Methods We performed a systematic review and meta-analysis (MEDLINE and E...

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Bibliographic Details
Main Authors: Filippo Sanfilippo, Joshua B. Knight, Sabino Scolletta, Cristina Santonocito, Federico Pastore, Ferdinando L. Lorini, Luigi Tritapepe, Andrea Morelli, Antonio Arcadipane
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Critical Care
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13054-017-1849-0