Structural Basis of pH Dependence of Neoculin, a Sweet Taste-Modifying Protein.

Among proteins utilized as sweeteners, neoculin and miraculin are taste-modifying proteins that exhibit pH-dependent sweetness. Several experiments on neoculin have shown that His11 of neoculin is responsible for pH dependence. We investigated the molecular mechanism of the pH dependence of neoculin...

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Bibliographic Details
Main Authors: Takayuki Ohkubo, Minoru Tamiya, Keiko Abe, Masaji Ishiguro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4444330?pdf=render