Co-transplantation of MRF-overexpressing oligodendrocyte precursor cells and Schwann cells promotes recovery in rat after spinal cord injury

Co-transplantation of MRF-overexpressing oligodendrocyte precursor cells and Schwann cells promotes recovery in rat after spinal cord injury

Oligodendrocyte (OL) replacement is a promising treatment strategy for spinal cord injury (SCI). However, the poor survival of transplanted OLs or their precursors and inhibition of axonal regeneration are two major challenges with this approach. Our previous study showed that Schwann cells (SCs) pr...

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Bibliographic Details
Main Authors: Xiu-Mei Xie, Ling-Ling Shi, Lin Shen, Rui Wang, Qi Qi, Qi-Yi Wang, Lun-Jun Zhang, He-Zuo Lü, Jian-Guo Hu
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Neurobiology of Disease
Subjects:
Myelin gene regulatory factor
OL progenitor cells
Schwann cells
Transplantation
Spinal cord injury
Functional recovery
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996116301577

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http://www.sciencedirect.com/science/article/pii/S0969996116301577

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