The Goto-Kakizaki rat is a spontaneous prototypical rodent model of polycystic ovary syndrome

Although polycystic ovary syndrome is the most common cause of female infertility, its etiology remains poorly understood. Here, the authors report a rat model that spontaneously exhibits the clinical heterogeneity of this syndrome and demonstrate that the phenotype is developmentally programmed.

Bibliographic Details
Main Authors: Camille Bourgneuf, Danielle Bailbé, Antonin Lamazière, Charlotte Dupont, Marthe Moldes, Dominique Farabos, Natacha Roblot, Camille Gauthier, Emmanuelle Mathieu d’Argent, Joelle Cohen-Tannoudji, Danielle Monniaux, Bruno Fève, Jamileh Movassat, Nathalie di Clemente, Chrystèle Racine
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21308-y