Replication study of ESCC susceptibility genetic polymorphisms locating in the ADH1B-ADH1C-ADH7 cluster identified by GWAS.

China was one of the countries with highest esophageal squamous cell carcinoma (ESCC) incidence and mortality worldwide. Alcohol drinking has been identified as a major environmental risk-factor related to ESCC. The alcohol dehydrogenase (ADH) family are major enzymes involved in the alcohol-metabol...

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Bibliographic Details
Main Authors: Jiwen Wang, Jinyu Wei, Xiaoling Xu, Wenting Pan, Yunxia Ge, Changchun Zhou, Chao Liu, Jia Gao, Ming Yang, Weimin Mao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3983154?pdf=render