Decellularized Adipose Tissue Hydrogel Promotes Bone Regeneration in Critical-Sized Mouse Femoral Defect Model

Decellularized Adipose Tissue Hydrogel Promotes Bone Regeneration in Critical-Sized Mouse Femoral Defect Model

Critical-sized bone defects fail to heal and often cause non-union. Standard treatments employ autologous bone grafting, which can cause donor tissue loss/pain. Although several scaffold types can enhance bone regeneration, multiple factors limit their level of success. To address this issue, this s...

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Bibliographic Details
Main Authors: Omair A. Mohiuddin, Brett Campbell, J. Nick Poche, Michelle Ma, Emma Rogers, Dina Gaupp, Mark A. A. Harrison, Bruce A. Bunnell, Daniel J. Hayes, Jeffrey M. Gimble
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
critical-sized femoral defect
decellularized adipose tissue hydrogel
adipose derived stromal/stem cells (ASC)
hydroxyapatite
histology
immunohistochemistry
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2019.00211/full

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https://www.frontiersin.org/article/10.3389/fbioe.2019.00211/full

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