Inhibition of inflammation by minocycline improves heart failure and depression-like behaviour in rats after myocardial infarction.

<h4>Rationale</h4>Patients with heart failure have an increased incidence of depression. Central and peripheral inflammation play a major role in the pathophysiology of both heart failure and depression.<h4>Aim</h4>Minocycline is an antibiotic that inhibits microglia activati...

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Bibliographic Details
Main Authors: Hong-Wei Wang, Monir Ahmad, Rami Jadayel, Fatimah Najjar, Diane Lagace, Frans H H Leenen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0217437