NKX6.1 Represses Tumorigenesis, Metastasis, and Chemoresistance in Colorectal Cancer

NKX6.1 Represses Tumorigenesis, Metastasis, and Chemoresistance in Colorectal Cancer

Accumulating evidence suggests that NKX6.1 (NK homeobox 1) plays a role in various types of cancer. In our previous studies, we identified <i>NKX6.1</i> hypermethylation as a promising marker and demonstrated that the NKX6.1 gene functions as a metastasis suppressor through the epigeneti...

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Bibliographic Details
Main Authors: Hsin-Hua Chung, Chun-Te Lee, Je-Ming Hu, Yu-Ching Chou, Ya-Wen Lin, Yu-Lueng Shih
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
NK6 homeobox 1 (NKX6.1)
colorectal cancer (CRC)
tumor suppressor
metastasis
epithelial-to-mesenchymal transition (EMT)
chemoresistance
Online Access:https://www.mdpi.com/1422-0067/21/14/5106

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https://www.mdpi.com/1422-0067/21/14/5106

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