Periostin plays a critical role in the cell cycle in lung fibroblasts

Periostin plays a critical role in the cell cycle in lung fibroblasts

Abstract Background Idiopathic pulmonary fibrosis (IPF) is a devastating disease with a median survival of only three to 5 years. Fibroblast proliferation is a hallmark of IPF as is secretion of extracellular matrix proteins from fibroblasts. However, it is still uncertain how IPF fibroblasts acquir...

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Bibliographic Details
Main Authors: Tomohito Yoshihara, Yasuhiro Nanri, Satoshi Nunomura, Yukie Yamaguchi, Carol Feghali-Bostwick, Keiichi Ajito, Shoichi Murakami, Masaaki Mawatari, Kenji Izuhara
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Respiratory Research
Subjects:
Idiopathic pulmonary fibrosis
Periostin
Fibroblast
Proliferation
Cell cycle
Integrin
Online Access:https://doi.org/10.1186/s12931-020-1299-0

Internet

https://doi.org/10.1186/s12931-020-1299-0

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