Gene expression noise in spatial patterning: hunchback promoter structure affects noise amplitude and distribution in Drosophila segmentation.

Gene expression noise in spatial patterning: hunchback promoter structure affects noise amplitude and distribution in Drosophila segmentation.

Positional information in developing embryos is specified by spatial gradients of transcriptional regulators. One of the classic systems for studying this is the activation of the hunchback (hb) gene in early fruit fly (Drosophila) segmentation by the maternally-derived gradient of the Bicoid (Bcd)...

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Bibliographic Details
Main Authors: David M Holloway, Francisco J P Lopes, Luciano da Fontoura Costa, Bruno A N Travençolo, Nina Golyandina, Konstantin Usevich, Alexander V Spirov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21304932/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21304932/?tool=EBI

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