HERG K+ channel-dependent apoptosis and cell cycle arrest in human glioblastoma cells.

HERG K+ channel-dependent apoptosis and cell cycle arrest in human glioblastoma cells.

Glioblastoma (GB) is associated with poor patient survival owing to uncontrolled tumor proliferation and resistance to apoptosis. Human ether-a-go-go-related gene K(+) channels (hERG; Kv11.1, KCNH2) are expressed in multiple cancer cells including GB and control cell proliferation and death. We hypo...

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Bibliographic Details
Main Authors: Ingo Staudacher, Julian Jehle, Kathrin Staudacher, Hans-Werner Pledl, Dieter Lemke, Patrick A Schweizer, Rüdiger Becker, Hugo A Katus, Dierk Thomas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24516604/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24516604/pdf/?tool=EBI

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