NLGN3 Upregulates Expression of ADAM10 to Promote the Cleavage of NLGN3 via Activating the LYN Pathway in Human Gliomas

The neuron derived synaptic adhesion molecular neuroligin-3 (NLGN3) plays an important role in glioma growth. While the role of autocrine NLGN3 in glioma has not been well-studied. The expression of NLGN3 in glioma was detected using immunohistochemistry. We further explored its function and regulat...

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Bibliographic Details
Main Authors: Ning-Ning Dang, Xiao-Bing Li, Mei Zhang, Chen Han, Xiao-Yong Fan, Shu-Hong Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
LYN
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.662763/full