Reduction-Triggered Paclitaxel Release Nano-Hybrid System Based on Core-Crosslinked Polymer Dots with a pH-Responsive Shell-Cleavable Colorimetric Biosensor

Reduction-Triggered Paclitaxel Release Nano-Hybrid System Based on Core-Crosslinked Polymer Dots with a pH-Responsive Shell-Cleavable Colorimetric Biosensor

Herein, we describe the fabrication and characterization of carbonized disulfide core-crosslinked polymer dots with pH-cleavable colorimetric nanosensors, based on diol dye-conjugated fluorescent polymer dots (L-PD), for reduction-triggered paclitaxel (PTX) release during fluorescence imaging-guided...

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Bibliographic Details
Main Authors: Seul Gi Kim, Benny Ryplida, Pham Thi My Phuong, Hyun Jeong Won, Gibaek Lee, Suk Ho Bhang, Sung Young Park
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
nano-hybrid matrix
polymer dots
controllable drug release
ph-sensitive
redox-responsive
Online Access:https://www.mdpi.com/1422-0067/20/21/5368

Internet

https://www.mdpi.com/1422-0067/20/21/5368

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