Identification of serotonin 2A receptor as a novel HCV entry factor by a chemical biology strategy

ABSTRACT Hepatitis C virus (HCV) is a leading cause of liver disease worldwide. Although several HCV protease/polymerase inhibitors were recently approved by U.S. FDA, the combination of antivirals targeting multiple processes of HCV lifecycle would optimize anti-HCV therapy and against potential dr...

Full description

Bibliographic Details
Main Authors: Lin Cao, Jizheng Chen, Yaxin Wang, Yuting Yang, Jie Qing, Zihe Rao, Xinwen Chen, Zhiyong Lou
Format: Article
Language:English
Published: SpringerOpen 2018-03-01
Series:Protein & Cell
Subjects:
HCV
Online Access:http://link.springer.com/article/10.1007/s13238-018-0521-z