Tungstate reduces the expression of gluconeogenic enzymes in STZ rats.

Oral administration of sodium tungstate has shown hyperglycemia-reducing activity in several animal models of diabetes. We present new insights into the mechanism of action of tungstate.We studied protein expression and phosphorylation in the liver of STZ rats, a type I diabetes model, treated with...

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Bibliographic Details
Main Authors: Laura Nocito, Delia Zafra, Joaquim Calbó, Jorge Domínguez, Joan J Guinovart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3414523?pdf=render