Interferon signaling patterns in peripheral blood lymphocytes may predict clinical outcome after high-dose interferon therapy in melanoma patients

<p>Abstract</p> <p>Background</p> <p>High-dose Interferon (HDI) therapy produces a clinical response and achieves relapse-free survival in 20-33% of patients with operable high risk or metastatic melanoma. However, patients may develop significant side effects frequentl...

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Bibliographic Details
Main Authors: Kirkwood John M, Lee Gerald, Simons Diana L, Lee Peter P
Format: Article
Language:English
Published: BMC 2011-05-01
Series:Journal of Translational Medicine
Subjects:
Online Access:http://www.translational-medicine.com/content/9/1/52