The role of purine metabolites as DAMPs in acute graft-versus-host disease.
Acute graft-versus-host disease (GVHD) causes high mortality in patients undergoing allogeneic hematopoietic cell transplantation (allo-HCT). An early event in the classical pathogenesis of acute GVHD is tissue damage caused by the conditioning treatment or infection that consecutively leads to tra...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2016-10-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00439/full |