Early-life exposure to benzo[a]pyrene increases mutant frequency in spermatogenic cells in adulthood.

Children are vulnerable to environmental mutagens, and the developing germline could also be affected. However, little is known about whether exposure to environmental mutagens in childhood will result in increased germline mutations in subsequent adult life. In the present study, male transgenic la...

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Bibliographic Details
Main Authors: Guogang Xu, C Alex McMahan, Christi A Walter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3906184?pdf=render