Transcriptional profile of fibroblasts obtained from the primary site, lymph node and bone marrow of breast cancer patients

Transcriptional profile of fibroblasts obtained from the primary site, lymph node and bone marrow of breast cancer patients

Cancer-associated fibroblasts (CAF) influence tumor development at primary as well as in metastatic sites, but there have been no direct comparisons of the transcriptional profiles of stromal cells from different tumor sites. In this study, we used customized cDNA microarrays to compare the gene exp...

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Bibliographic Details
Main Authors: Paulo Roberto Del Valle, Cintia Milani, Maria Mitzi Brentani, Maria Lucia Hirata Katayama, Eduardo Carneiro de Lyra, Dirce Maria Carraro, Helena Brentani, Renato Puga, Leandro A. Lima, Patricia Bortman Rozenchan, Bárbara dos Santos Nunes, João Carlos Guedes Sampaio Góes, Maria Aparecida Azevedo Koike Folgueira
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2014-09-01
Series:Genetics and Molecular Biology
Subjects:
bone marrow
breast neoplasm
fibroblast
gene expression profiling
lymph node
mesenchymal stromal cells
tumor microenvironment
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572014000400002&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572014000400002&lng=en&tlng=en

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